… evidence of mitochondria’s role in differentiation … differentiation-inducing factors (DIF) (Kubohara
et al., 2017, Thompson and Kay, 2000). These DIFs also are involved in chemotaxis in D…

… differentially control stalk cell differentiation and chemotaxis. We … have at least three receptors:
DR-1D, responsible for stalk cell … to mitochondria, suggesting that DIF-1 controls stalk cell …

… differentiation, cell death, chemotaxis, and morphogenesis, … isolated as a stalk cell
differentiation-inducing factor in D. … a mitochondrial uncoupler and can promote glucose uptake, at …

… produced by Dictyostelium discoideum that inhibits the … exhausted, unicellular cells
differentiate into multicellular fruiting … was performed using anti-HA antibody or control mouse IgG …

… Differentiation-inducing factor-1 (DIF-1) is a polyketide produced by Dictyostelium discoideum
… mammalian cells, at least in part by activating AMP-activated protein kinase (AMPK). In a …

… characterized by chemotaxis, morphogenesis and cell differentiation. … discoideum has three
NDPK genes (mitochondrial ndkM, … role of differentiation inducing factor-1 (DIF-1) in stalk cell …

… , chemoattractant cyclic AMP relay leads to cell streaming … Evidence has also been provided
that microtubules control … The finding that mitochondrial respiratory deficiencies induce …

… Deletion mutations in mitochondrial DNA are considered as a hallmark … discoideum is
instrumented to study chemotaxis and … Differentiation-inducing factor (DIF) triggers cell death only …

… acts at a central control point in cellular energy homeostasis. … of Dictyostelium cells to
differentiation-inducing factor-1 (DIF-… There is an increasing body of evidence of the intrinsic …

… We describe evidence suggesting that overexpressing … the prespore pathways of cell
differentiation may depend on the … in strains with defective mitochondrial function, which is thought …